The epigenomic matrix of tissue-specific immune memory
- PMID: 39260353
- DOI: 10.1016/j.immuni.2024.08.009
The epigenomic matrix of tissue-specific immune memory
Abstract
Tissue-resident memory CD8+ T cells serve as a first-line defense against many pathogens. In this issue of Immunity, Buquicchio et al. unveil the epigenomic landscapes of virus-specific CD8+ T cell subsets, highlighting common and organ-specific regulators driving their differentiation.
Copyright © 2024. Published by Elsevier Inc.
Conflict of interest statement
Declaration of interests M.B. is a consultant for Bristol Myers Squibb, Mabtech, Pfizer, Gilead, and MSD.
Comment on
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Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation.Immunity. 2024 Sep 10;57(9):2202-2215.e6. doi: 10.1016/j.immuni.2024.06.014. Epub 2024 Jul 22. Immunity. 2024. PMID: 39043184
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