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. 2024 Sep 11;24(1):482.
doi: 10.1186/s12872-024-04136-y.

Trends in deaths and disability-adjusted life-years of ischemic heart disease attributable to high body-mass index worldwide, 1990-2019

Wei Yan  1 , Yajun Hua  2
Affiliations

Trends in deaths and disability-adjusted life-years of ischemic heart disease attributable to high body-mass index worldwide, 1990-2019

Wei Yan et al. BMC Cardiovasc Disord. .

Abstract

Background: The objective of this study is to evaluate the global burden of ischemic heart disease (IHD) attributable to High body mass index (HBMI) by utilizing data from Global Burden of Disease (GBD) 2019.

Methods: This study utilized data from the GBD 2019 to examine the impact of HBMI on deaths and disability-adjusted life years (DALYs). The analysis focused on age-standardized rates and considered a 30-year time frame. Trends were assessed using estimated annual percentage changes (EAPCs).

Results: Since 1990, a significant global increase in IHD attributable to HBMI has been observed. This increase is particularly notable among elderly males and in regions with low-middle Socio-Demographic Index (SDI), such as Central Asia and Eastern Europe. In 2019, IHD globally resulted in 1,662,339 deaths and 41,369,773 DALYs. Despite the high age-standardized death rate (20.73 per 100,000) and DALY rate (499.41 per 100,000), a declining trend was noted. This trend is reflected by the EAPCs of -0.35 for DALYs and - 0.67 for deaths. Notably, males and middle SDI countries exhibited higher rates of IHD, whereas high SDI regions such as High-income Asia Pacific and Western Europe showed decreasing trends in IHD.

Conclusion: Over the past three decades, there has been a significant increase in IHD caused by HBMI, especially in low-middle and low SDI regions. This highlights the importance of targeted interventions in addressing this issue. Notably, regions including Central Asia, Eastern Europe, North Africa, and the Middle East have been heavily affected.

Keywords: EAPC; High body mass index; Ischemic heart disease; Socio-Demographic Index.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
The Global Burden of ischemic heart disease attributable to high body-mass index: age-standardized DALY rate and ASDR in 1990 and 2019: (A) ASDR in 1990; (B) age-standardized DALY rate in 1990; (C) ASDR in 2019; (D) age-standardized DALY rate in 2019; (E) EAPCs of ASDR; (F) EAPCs of age-standardized DALY rate. ASRs = age-standardized rates. ASDR = age-standardized Death rate. DALY = disability adjusted life-year. EAPCs = Estimated Annual Percentage Changes
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