Valproate-Autism Labyrinth
- PMID: 39263199
- PMCID: PMC11385261
Valproate-Autism Labyrinth
Abstract
Valproate and Autism complexity is manifold. From an established environmental risk factor for autism, to a translational animal model, valproate's composite mode of action might unfold to address core autistic domains transcending mere aggressive behavioural control.
Keywords: autism; folic acid; irritability; risk; translational model; valproate.
Copyright © 1964–2024 by MedWorks Media Inc, Los Angeles, CA All rights reserved. Printed in the United States.
Similar articles
-
Intravenous valproate for rapid stabilization of agitation in neuropsychiatric disorders.J Neuropsychiatry Clin Neurosci. 1998 Summer;10(3):365-6. doi: 10.1176/jnp.10.3.365. J Neuropsychiatry Clin Neurosci. 1998. PMID: 9706547 No abstract available.
-
Assessment of behavioral, morphological and electrophysiological changes in prenatal and postnatal valproate induced rat models of autism spectrum disorder.Sci Rep. 2021 Dec 6;11(1):23471. doi: 10.1038/s41598-021-02994-6. Sci Rep. 2021. PMID: 34873263 Free PMC article.
-
Effects of Cannabidiol Isolated or in Association With Risperidone in an Animal Model of Autism.Dev Neurobiol. 2025 Jan;85(1):e22955. doi: 10.1002/dneu.22955. Dev Neurobiol. 2025. PMID: 39604124
-
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.Cochrane Database Syst Rev. 2017 Feb 14;2(2):CD003032. doi: 10.1002/14651858.CD003032.pub3. Cochrane Database Syst Rev. 2017. Update in: Cochrane Database Syst Rev. 2019 Feb 08;2:CD003032. doi: 10.1002/14651858.CD003032.pub4. PMID: 28195639 Free PMC article. Updated.
-
Pharmacological intervention for irritability, aggression, and self-injury in autism spectrum disorder (ASD).Cochrane Database Syst Rev. 2023 Oct 9;10(10):CD011769. doi: 10.1002/14651858.CD011769.pub2. Cochrane Database Syst Rev. 2023. PMID: 37811711 Free PMC article.
References
-
- Taleb A, Lin W, Xu X et al. Emerging mechanisms of valproic acid-induced neurotoxic events in autism and its implications for pharmacological treatment. Biomed Pharamcother . 2021;137:111322. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources