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. 2024 Nov;26(11):5202-5210.
doi: 10.1111/dom.15866. Epub 2024 Sep 12.

Impact of continuous glucose monitoring on hospitalizations and glucose control in people with type 2 diabetes: real-world analysis

Satish K Garg  1 , Irl B Hirsch  2 , Enrico Repetto  3 , Janet Snell-Bergeon  1 , Brian Ulmer  3 , Christopher Perkins  3 , Richard M Bergenstal  4
Affiliations

Impact of continuous glucose monitoring on hospitalizations and glucose control in people with type 2 diabetes: real-world analysis

Satish K Garg et al. Diabetes Obes Metab. 2024 Nov.

Abstract

Aim: The real-world benefits of continuous glucose monitoring (CGM) in the broad type 2 diabetes (T2D) population are not well studied. Our study evaluated the impact of CGM use on health care resource utilization over 12 months in adults with T2D.

Materials and methods: This retrospective cohort analysis used Optum's de-identified Market Clarity data of >79 million people to evaluate CGM use in people with T2D who were treated with non-insulin (NIT), basal insulin (BIT) and prandial insulin therapy (PIT). The primary outcomes were changes in all-cause hospitalizations, acute diabetes-related hospitalizations and acute diabetes-related emergency room visits during the 6- and 12-month post-index period following transition from blood glucose monitoring to CGM. A pre-specified subgroup analysis assessed glucose control and medication changes among people with T2D over 1 year.

Results: The analysis included 74 679 adults with T2D (NIT; n = 25 269), (BIT; n = 16 264) and (PIT; n = 33 146). Significant reductions in all-cause hospitalizations, acute diabetes-related hospitalizations and acute diabetes-related emergency room visits were observed in the 6-month post-index period that were sustained during the 6-12 month post-index period (NIT, -10.1%, -31.0%, -30.7%; BIT, -13.9%, -47.6%, -28.2%; and PIT, -22.6%, -52.7%, -36.6%, respectively). A subgroup analysis of 6030 people showed mean glycated haemoglobin reductions at approximately 3 months, which were also sustained throughout the post-index period: NIT, -1.1 (0.05)%; BIT, -1.1 (0.06)%; and PIT, -0.9 (0.04)%, p < 0.0001.

Conclusions: CGM use in real-life across different therapeutic regimens in adults with T2D was associated with reductions in health care resource utilization with improved glucose control over 1 year.

Keywords: continuous glucose monitoring; diabetes‐related events; hospitalizations; insulin; multiple daily injections; non‐insulin.

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References

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