Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug;177(4):476-481.
doi: 10.1007/s10517-024-06211-y. Epub 2024 Sep 12.

Biofilm Formation by Lactobacillus Strains of Modern Probiotics and Their Antagonistic Activity against Opportunistic Bacteria

O A Svitich  1 , A V Poddubikov  2 , N O Vartanova  1 , A Yu Leonova  1 , E A Kurbatova  1
Affiliations

Biofilm Formation by Lactobacillus Strains of Modern Probiotics and Their Antagonistic Activity against Opportunistic Bacteria

O A Svitich et al. Bull Exp Biol Med. 2024 Aug.

Abstract

The species identity of the studied lactobacillus strains was confirmed by matrix-activated laser desorption/ionization with time-of-flight ion separation (MALDI-TOF mass spectrometry). Lactobacillus strains differed in the dynamics of lactic acid accumulation and changes in the pH of the culture medium. The culture medium affected adhesion ability of lactobacilli. The ability to adhere does not affect the formation of biofilms by lactobacillus strains except for the L. acidophilus La5 strain, which has low adhesion ability and fewer microbial cells detected after mechanical destruction of the biofilm. The metabiotics of the lactobacillus culture medium have an antagonistic effect on conditionally pathogenic microorganisms. Adhesion, biofilm formation, and antagonistic activity of probiotic lactobacillus strains are strain-specific properties.

Keywords: Lactobacillus; adhesion; antagonism; biofilm; lactic acid.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Mokoena MP, Omatola CA, Olaniran AO. Applications of lactic acid bacteria and their bacteriocins against food spoilage microorganisms and foodborne pathogens. Molecules. 2021;26(22):7055. https://doi.org/10.3390/molecules26227055 - DOI - PubMed - PMC
    1. Kannappan A, Balasubramaniam B, Ranjitha R, Srinivasan R, Packiavathy IASV, Balamurugan K, Pandian SK, Ravi AV. In vitro and in vivo biofilm inhibitory efficacy of geraniol-cefotaxime combination against Staphylococcus spp. Food Chem. Toxicol. 2019;125:322-332. https://doi.org/10.1016/j.fct.2019.01.008 - DOI - PubMed
    1. Kim JH, Lee ES, Song KJ, Kim BM, Ham JS, Oh MH. Development of desiccation-tolerant probiotic biofilms inhibitory for growth of foodborne pathogens on stainless steel surfaces. Foods. 2022;11(6):831. https://doi.org/10.3390/foods11060831 - DOI - PubMed - PMC
    1. Mgomi FC, Yang YR, Cheng G, Yang ZQ. Lactic acid bacteria biofilms and their antimicrobial potential against pathogenic microorganisms. Biofilm. 2023;5:100118. https://doi.org/10.1016/j.bioflm.2023.100118 - DOI - PubMed - PMC
    1. Nguyen PT, Nguyen TT, Bui DC, Hong PT, Hoang QK, Nguyen HT. Exopolysaccharide production by lactic acid bacteria: the manipulation of environmental stresses for industrial applications. AIMS Microbiol. 2020;6(4):451-469. https://doi.org/10.3934/microbiol.2020027 - DOI - PubMed - PMC

MeSH terms

LinkOut - more resources