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. 1985 Jun;76(6):425-8.

Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline

F Ishikawa, F Takaku, M Nagao, M Ochiai, K Hayashi, S Takayama, T Sugimura
  • PMID: 3926575

Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline

F Ishikawa et al. Jpn J Cancer Res. 1985 Jun.

Abstract

The presence of activated oncogenes in several rat hepatocellular carcinomas induced by 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) was examined by NIH 3T3 cell transfection assay and Southern blot analysis. In one tumor, IQ4, rat H-ras-1 and another oncogene that did not belong to the ras family were found to be activated.

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