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Case Reports
. 2025 May;41(5):1109-1123.
doi: 10.1080/09593985.2024.2393213. Epub 2024 Sep 12.

Cognitive Multisensory Rehabilitation, a novel approach for Complex Regional Pain Syndrome: case series

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Free article
Case Reports

Cognitive Multisensory Rehabilitation, a novel approach for Complex Regional Pain Syndrome: case series

Marc A Pique Batalla et al. Physiother Theory Pract. 2025 May.
Free article

Abstract

Introduction: Effective treatment for Complex Regional Pain Syndrome (CRPS), a chronic pain condition, is challenging. Cognitive Multisensory Rehabilitation (CMR) is a cognitive and sensorimotor treatment approach aimed at restoring function that targets cognitive, somatosensory, and multisensory functions through sensory discrimination tasks.

Purpose: We aimed to apply CMR to treat CRPS within our clinical practice. Clinically, we have found promising results in reducing pain and other common features of CRPS, such as Body Perception Disturbances (BPD).

Methods: In this clinical case series, four CRPS patients who participated in a two-week interdisciplinary CRPS rehabilitation program at the National Complex Regional Pain Syndrome Service in Bath, UK received CMR as part of their treatment. A combination of self-reported measures and clinical outcomes were collected pre and post-rehabilitation program.

Results: Functional improvements and a reduction on BPD were observed in all clinical cases.

Discussion: We demonstrate how CMR may improve several CRPS-related features that often hinder rehabilitation in people living with CRPS.

Conclusion: Research involving larger cohorts are necessary to provide empirical evidence of the application of CMR in treating CRPS.

Keywords: Cognitive multisensory rehabilitation; chronic pain treatment; complex regional pain syndrome; occupational therapy; physical therapy.

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