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Review
. 2025;55(8):1702-1722.
doi: 10.1080/10408347.2024.2399202. Epub 2024 Sep 13.

Safeguarding Public Health: Advanced Detection of Food Adulteration Using Nanoparticle-Based Sensors

Affiliations
Review

Safeguarding Public Health: Advanced Detection of Food Adulteration Using Nanoparticle-Based Sensors

Muthu Thiruvengadam et al. Crit Rev Anal Chem. 2025.

Abstract

Food adulteration, whether intentional or accidental, poses a significant public health risk. Traditional detection methods often lack the precision required to detect subtle adulterants that can be harmful. Although chromatographic and spectrometric techniques are effective, their high cost and complexity have limited their widespread use. To explore and validate the application of nanoparticle-based sensors for enhancing the detection of food adulteration, focusing on their specificity, sensitivity, and practical utility in the development of resilient food safety systems. This study integrates forensic principles with advanced nanomaterials to create a robust detection framework. Techniques include the development of nanoparticle-based assays designed to improve the detection specificity and sensitivity. In addition, sensor-based technologies, including electronic noses and tongues, have been assessed for their capacity to mimic and enhance human sensory detection, offering objective and reliable results. The use of nanomaterials, including functionalized nanoparticles, has significantly improved the detection of trace amounts of adulterants. Nanoparticle-based sensors demonstrate superior performance in terms of speed, sensitivity, and selectivity compared with traditional methods. Moreover, the integration of these sensors into food safety protocols shows promise for real-time and onsite detection of adulteration. Nanoparticle-based sensors represent a cutting-edge approach for detecting food adulteration, and offer enhanced sensitivity, specificity, and scalability. By integrating forensic principles and nanotechnology, this framework advances the development of more resilient food-safety systems. Future research should focus on optimizing these technologies for widespread application and adapting them to address emerging adulteration threats.

Keywords: DNA-based techniques; food adulteration; food forensics; nanomaterials; sensors.

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