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Case Reports
. 2024 Sep 13;14(3).
doi: 10.2106/JBJS.CC.24.00025. eCollection 2024 Jul 1.

Immobile to Ambulation: Complex Multijoint Pathologies in a Patient with Advanced HIV Disease: A Case Report

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Case Reports

Immobile to Ambulation: Complex Multijoint Pathologies in a Patient with Advanced HIV Disease: A Case Report

Justin T Samuel et al. JBJS Case Connect. .

Abstract

Case: A 30-year-old man with a history of advanced HIV disease (AHD) presented with bilateral equinocavus, leg, and foot muscle paresis, Brooker grade 4 heterotopic ossification of hips and knee stiffness, and was unable to sit upright, stand independently, or walk. Electromyography showed demyelinating sensorimotor and axonal polyneuropathy of lower extremities. Multiple surgeries of bilateral hips, ankles, and feet enabled joint mobility, plantigrade feet, and independent ambulation.

Conclusion: Patients with AHD may develop multijoint pathologies, secondary to HIV, antiretroviral therapy, or prolonged immobility, resulting in loss of ambulation and independence. Restoring ambulation may necessitate multiple surgeries, with potential for success.

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Conflict of interest statement

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/C435).

References

    1. Lehman A, Ellis J, Nalintya E, Bahr NC, Loyse A, Rajasingham R. Advanced HIV disease: a review of diagnostic and prophylactic strategies. HIV Med. 2023;24(8):859-76.
    1. Berg LS, Young JJ, Kopansky-Giles D, Eberspaecher S, Outerbridge G, Hurwitz EL, Hartvigsen J. Musculoskeletal conditions in persons living with HIV/AIDS: a scoping review. Curr Med Sci. 2022;42(1):17-25.
    1. Tehranzadeh J, Ter-Oganesyan RR, Steinbach LS. Musculoskeletal disorders associated with HIV infection and AIDS. Part I: infectious musculoskeletal conditions. Skeletal Radiol. 2004;33(5):249-59.
    1. Hoke M. An operation for the correction of extremely relaxed flatfeet. J Bone Joint Surg. 1931;13:773-83.
    1. Mohan A, Tarras S, Eckardt PA. HIV neuropathy-associated foot drop, a presenting sign of HIV infection, resolving after initiation of antiretroviral therapy: a clinical vignette. Am J Phys Med Rehabil. 2021;100(7):e94-e97.

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