Response to Wynn and Hokovec Regarding "The Use of cfDNA to Screen for Monogenic Conditions in Low Risk Populations Is Ready for Clinical Use"

Affiliations

¹ Reproductive Genetics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
² Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
³ Genetics and Genomic Medicine, UCL Institute of Child Health and Great Ormond Street NHS Foundation Trust, London, UK.

Comment

Neeta L Vora et al. Prenat Diagn. 2024 Nov.

. 2024 Nov;44(12):1500-1501.

doi: 10.1002/pd.6656. Epub 2024 Sep 14.

¹ Reproductive Genetics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
² Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
³ Genetics and Genomic Medicine, UCL Institute of Child Health and Great Ormond Street NHS Foundation Trust, London, UK.

No abstract available

Comment on

Current controversy in prenatal diagnosis: The use of cfDNA to screen for monogenic conditions in low risk populations is ready for clinical use.
Vora NL, Langlois S, Chitty LS. Vora NL, et al. Prenat Diagn. 2024 Apr;44(4):389-397. doi: 10.1002/pd.6469. Epub 2023 Nov 22. Prenat Diagn. 2024. PMID: 37991340 Review.
Correspondence on "Current Controversy in Prenatal Diagnosis: The Use of cfDNA to Screen for Monogenic Conditions in Low Risk Populations Is Ready for Clinical Use".
Wynn J, Hoskovec J. Wynn J, et al. Prenat Diagn. 2024 Nov;44(12):1498-1499. doi: 10.1002/pd.6655. Epub 2024 Sep 14. Prenat Diagn. 2024. PMID: 39275898 No abstract available.

1. N. L. Vora, S. Langlois, and L. S. Chitty, “Current Controversy in Prenatal Diagnosis: The Use of cfDNA to Screen for Monogenic Conditions in Low Risk Populations is Ready for Clinical Use,” Prenatal Diagnosis 44 (2024): 389–397, https://doi.org/10.1002/pd.6469. PMID: 37991340.
1. J. Hoskovec, E. E. Hardisty, A. N. Talati, et al., “Maternal Carrier Screening With Single‐Gene NIPS Provides Accurate Fetal Risk Assessments for Recessive Conditions,” Genetics in Medicine 25, no. 2 (2022): 1–103, https://doi.org/10.1016/j.gim.2022.10.014.
1. J. Wynn, J. Hoskovec, R. D. Carter, M. J. Ross, and S. C. Perni, “Performance of Single‐Gene Noninvasive Prenatal Testing for Autosomal Recessive Conditions in a General Population Setting,” Prenatal Diagnosis 43, no. 10 (September 2023): 1344–1354, https://doi.org/10.1002/pd.6427.