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Editorial
. 2024 Aug 31;15(4):2002-2005.
doi: 10.21037/jgo-24-255. Epub 2024 Aug 5.

MRTX1133's promise for treating KRASG12D-mutant pancreatic cancer

Affiliations
Editorial

MRTX1133's promise for treating KRASG12D-mutant pancreatic cancer

Malak Haidar et al. J Gastrointest Oncol. .
No abstract available

Keywords: KRAS; MRTX1133; Pancreatic ductal adenocarcinoma (PDAC).

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Conflict of interest statement

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://jgo.amegroups.com/article/view/10.21037/jgo-24-255/coif). M.H. is a Research Assistant at the Fonds de la Recherche Scientifique (FNRS) FRS-FNRS. P.J. is a Research Director at FRS-FNRS. The authors have no other conflicts of interest to declare.

Comment on

References

    1. Halbrook CJ, Lyssiotis CA, Pasca di Magliano M, et al. Pancreatic cancer: Advances and challenges. Cell 2023;186:1729-54. 10.1016/j.cell.2023.02.014 - DOI - PMC - PubMed
    1. Ushio J, Kanno A, Ikeda E, et al. Pancreatic Ductal Adenocarcinoma: Epidemiology and Risk Factors. Diagnostics (Basel) 2021;11:562. 10.3390/diagnostics11030562 - DOI - PMC - PubMed
    1. Bailey P, Chang DK, Nones K, et al. Genomic analyses identify molecular subtypes of pancreatic cancer. Nature 2016;531:47-52. 10.1038/nature16965 - DOI - PubMed
    1. Aung KL, McWhirter E, Welch S, et al. A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma. J Gastrointest Oncol 2022;13:3216-26. 10.21037/jgo-22-86 - DOI - PMC - PubMed
    1. Linehan A, O'Reilly M, McDermott R, et al. Targeting KRAS mutations in pancreatic cancer: opportunities for future strategies. Front Med (Lausanne) 2024;11:1369136. 10.3389/fmed.2024.1369136 - DOI - PMC - PubMed