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. 2024 Aug 13;16(8):e66821.
doi: 10.7759/cureus.66821. eCollection 2024 Aug.

Comparison of Knowledge About Induced Pluripotent Stem Cells in Relation to Gender Among Healthcare Professionals and in the General Population

Jasna M Gacic  1 , Sanja R Rascanin  2 , Mirjana R Jovanovic  2   3 , Srdjan S Nikolovski  4 , Nina Jovanovic  5 , Jelena Petkovic  6 , Nebojsa Zdravkovic  2 , Olivera Djokic  7 , Nemanja K Rancic  8
Affiliations

Comparison of Knowledge About Induced Pluripotent Stem Cells in Relation to Gender Among Healthcare Professionals and in the General Population

Jasna M Gacic et al. Cureus. .

Abstract

Introduction: Induced pluripotent stem cells (iPSCs) are derived by reprogramming adult somatic cells using a forced expression of four specific transcription factors in a highly controlled artificial environment. The aim of this paper is to examine the knowledge about these cells of the general population and the population of health workers in relation to gender.

Methods: The research was designed as a cohort study conducted with a validated questionnaire to assess knowledge about iPSCs. Respondents were people over 18 years of age on the territory of the cities of Belgrade and Kragujevac in Serbia.

Results: The study surveyed a total of 1,047 respondents, 560 (53.5%) women and 487 (46.5%) men. Statistically significant differences were observed for both genders. Women from both populations were better informed, more often agreed to treatment with iPSCs, more often supported further research, and were willing to take further education about iPSCs.

Conclusion: Comparing men and women from both populations, we found that men and women health workers showed greater knowledge compared to the general population. Level of knowledge and attitudes of the public can have multiple effects on further research emphasizing the importance of the support of public opinion about this type of treatment.

Keywords: gender; induced pluripotent stem cells; knowledge; questionnaire; stem cells.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Ethics Committee of Faculty of Medical Sciences, University of Kragujevac and Ethics Committee of Clinical Center Kragujevac issued approval 01-3148; March 19th, 2019 and 01119-1218; March 21st, 2019. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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