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Review
. 2024 Aug 28:26:635-645.
doi: 10.1016/j.reth.2024.08.015. eCollection 2024 Jun.

Recent advances in hydrogels applications for tissue engineering and clinical trials

Leila Rezakhani  1   2 , Maliheh Gharibshahian  3   4 , Majid Salehi  5 , Sepehr Zamani  6 , Zahra Abpeikar  7 , Omid Ghaderzadeh  8 , Morteza Alizadeh  9 , Alireza Masoudi  10 , Nariman Rezaei  6 , Danial Cheraghali  11
Affiliations
Review

Recent advances in hydrogels applications for tissue engineering and clinical trials

Leila Rezakhani et al. Regen Ther. .

Abstract

Hydrogels are biomolecules made of artificial and natural polymers. Their quasi-three-dimensional structure has created unique features. They are very hydrophilic, and in addition to the high inflation rate, they also have excellent water maintenance capacity, biodegradability, biocompatibility, and strong mechanical properties. These properties are used in many tissue engineering applications. All these features have made these scaffolds widely used as attractive structures in the world of tissue engineering and regeneration medicine. In addition to research, scaffolds entered the field of medicine and are expected to play a significant role in the repair of many tissues in the future. This study aims to review the various polymers involved in hydrogel fabrication and their application in the repair of diverse tissues and clinical trials.

Keywords: Clinical trials; Hydrogels; Regenerative medicine; Tissue engineering.

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Conflict of interest statement

The authors declare no conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Fig. 1
Fig. 1
Cell isolation for made bio scaffold in skin tissue engineering.
Fig. 2
Fig. 2
Preparation of hydrogel for wound healing application.
Fig. 3
Fig. 3
Application of hydrogel for bone regeneration.
Fig. 4
Fig. 4
Application of hydrogel in drug delivery.
See this image and copyright information in PMC

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