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. 2024 Aug 17;10(17):e36480.
doi: 10.1016/j.heliyon.2024.e36480. eCollection 2024 Sep 15.

The role of MRI in "estimating" intraoperative bleeding during cesarean section for placenta accreta: A prospective cohort study

Shimao Zhang  1 , Xin Li  2 , Ying Jin  1 , Linbo Cheng  1 , Tenglan Wu  1 , Xi Hou  3 , Sumei Wei  1 , Yalan Li  4 , Xue Xiao  2 , Tianjiao Liu  1 , Luying Wang  1
Affiliations

The role of MRI in "estimating" intraoperative bleeding during cesarean section for placenta accreta: A prospective cohort study

Shimao Zhang et al. Heliyon. .

Abstract

Objectives: The prenatal detection of placenta accreta spectrum (PAS) disorder is crucial for treatment strategy formulation. MRI descriptors may offer a more objective method for predicting PAS and clinical outcomes. The aim of this study is to investigate the predictive value of MRI examination for intraoperative blood loss in PAS cesarean section and elucidating the MRI descriptors that are more valuable for predicting intraoperative blood loss.

Methods: A prospective study was carried out on 164 pregnant women diagnosed with PAS. Maternal and neonatal perioperative characteristics were systematically collected. To evaluate the relationship between maternal and perioperative characteristics and intraoperative blood loss, as well as the predictive value of MRI descriptors on intraoperative blood loss, a multivariable linear regression analysis was performed.

Results: Patients were pre-grouped based on a combined ultrasound-MRI evaluation, with 108 cases (65.9 %) classified as placenta accreta, 47 cases (28.7 %) as placenta increta, and 9 cases (5.4 %) as placenta percreta. The results demonstrated that intraoperative blood loss was positively associated with partial MRI descriptors (F = 9.751, df = 15), such as placenta accreta (OR: 243.33, p = 0.006), cross-border blood vessels that pass through the uterine muscle layer (OR: 297.76, p = 0.012), interruption of hyperechoic uterus-bladder interface (bladder line) (OR: 342.59, p = 0.011), and subplacental hypervascularity (OR: 365.96, p = 0.027).

Conclusions: Preoperative MRI demonstrates promising predictive capabilities in estimating intraoperative blood loss for PAS patients. Pregnant women identified as having a high risk of intraoperative bleeding based on MRI findings should undergo closer antenatal monitoring in late pregnancy, along with more comprehensive preoperative blood preparation, to better ensure maternal and fetal safety.

Keywords: Intraoperative bleeding; MRI; Placenta accreta spectrum; Pregnant women; Prospective study.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
The selection process for this study.
Fig. 2
Fig. 2
Association between perioperative characteristics and intraoperative bleeding volume by multiple linear regression analysis. A) After adjusting for maternal age, pre-pregnancy BMI, gestational age, anemia, and incision direction, the results showed a significant correlation between intraoperative blood loss and ultrasound placental score, duration of surgery, preoperative balloon occlusion, emergency cesarean section, and PAS type; B) The amount of intraoperative bleeding was significantly different among placenta accreta, increta, and percreta groups (p < 0.001 Accreta vs Increta; p = 0.002 Increta vs Percreta).
See this image and copyright information in PMC

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