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Case Reports
. 2024 Aug 22:55:101489.
doi: 10.1016/j.gore.2024.101489. eCollection 2024 Oct.

Management of high-grade ovarian adenocarcinoma in an intraperitoneal pelvic renal transplant recipient

Esra Demirel  1 , Seth Cohen  2 , Ronald D Ennis  3 , Farr R Nezhat  4   5   6
Affiliations
Case Reports

Management of high-grade ovarian adenocarcinoma in an intraperitoneal pelvic renal transplant recipient

Esra Demirel et al. Gynecol Oncol Rep. .

Abstract

Background: Number of organ transplant recipients continues to rise worldwide with increasing accessibility and growing advancements in transplant medicine. Transplant patients have at least a two-to-four fold higher risk of developing cancer compared to the general population. As the prevalence of transplant patients increases, a growing number of these patients are expected to present with concurrent conditions such as cancer, requiring more complex and interdisciplinary care.

Case: A 44-year-old patient with an intraperitoneal pelvic renal transplant, found to have high-grade ovarian adenocarcinoma most likely arising from endometriosis, successfully underwent surgical staging, adjuvant chemotherapy, and subsequent pelvic radiation for recurrence. Her kidney function and graft viability were preserved throughout her treatment with careful monitoring.

Conclusion: Management of reproductive tract cancers in kidney transplant recipients is complex. Current practices largely rely on evidence from observational studies and case reports for these cancers and more research is needed in this area.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
(A) Laparoscopic view of transplanted intraperitoneal kidney (B) Native right ureter at pelvic brim (arrow).
Fig. 2
Fig. 2
(A) Retroverted uterus with endometrial echo measuring 1.7 cm. (B) Left lateral intramural leiomyoma (C) 1.4 complex cyst in right ovary, suggestive of a hemorrhagic cyst or endometrioma (D) 3.4 cm lobulated complex cyst in left ovary containing a possible involuting follicle.
Fig. 3
Fig. 3
PET CT images of coronal (A) and sagittal (B) views showing an enlarged lymph node in the right external iliac chain associated with increased hypermetabolic activity, concerning for nodal metastatic disease.
See this image and copyright information in PMC

References

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