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Review
. 2024 Sep;64(3):859-866.
doi: 10.1007/s12088-024-01315-5. Epub 2024 Jul 24.

SeqCode: A Nomenclatural Code for Prokaryotes

Affiliations
Review

SeqCode: A Nomenclatural Code for Prokaryotes

Pushp Lata et al. Indian J Microbiol. 2024 Sep.

Abstract

SeqCode is a nomenclatural code for naming prokaryotes based on genetic information. With the majority of prokaryotes being inaccessible as pure cultures, they are not eligible for naming under the International Code of Nomenclature of Prokaryotes. To address this challenge, a new concept that is SeqCode, which assign names to prokaryotes on the basis of genome sequence, has been announced in 2022. The valid publication of names for prokaryotes based on isolated genome, metagenome-assembled genomes, or single-amplified genome sequences. It operates through a registration portal, SeqCode Registry, where metadata is linked to names and nomenclatural types. This code provides a framework for reproducible nomenclature for all prokaryotes, either culturable or not and facilitates communication across all microbiological disciplines. Additionally, the SeqCode includes provisions for updating and revising names as new data becomes available. By providing a standardized system for naming and classifying these microorganisms based on their genetic information, the SeqCode will facilitate the discovery, understanding and comparison of these microorganisms, helping us to understand their role in the environment and how they contribute to the functioning of the Earth.

Keywords: ICNP; SeqCode; Taxonomy; Uncultured prokaryotes.

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Figures

Fig. 1
Fig. 1
Showing the need of the SeqCode. As INCP cannot name 99% of prokaryotes, a new code of nomenclature is required which is internationally accepted
Fig. 2
Fig. 2
Showing the decentralized nature of SeqCode Committee and its various bodies
Fig. 3
Fig. 3
Blueprint of development of SeqCode Registry
Fig. 4
Fig. 4
Paths of naming under SeqCode. Path 1 involves naming of one newly published name. Path 2 involves correction of already published names including Candidatus names
Fig. 5
Fig. 5
Showing the Standard Operating Procedure used when a manuscript is submitted to SeqCode Registry [9]

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