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. 2024 Aug 23:7:100198.
doi: 10.1016/j.crphar.2024.100198. eCollection 2024.

GERD: Latest update on acid-suppressant drugs

Zyad Al-Frejat  1   2 , Nafiza Martini  2   3 , Alia Esper  1   3 , Diana Al-Frejat  2   4 , Samer Younes  5   3 , Majd Hanna  2   3
Affiliations

GERD: Latest update on acid-suppressant drugs

Zyad Al-Frejat et al. Curr Res Pharmacol Drug Discov. .

Abstract

GERD is a very familiar diagnosis among health care providers due to its massive spread, and its symptoms can affect the quality of life for a respectable slice of its patients. Therefore, what can only be described as a logical consequence, a pursuit of a treatment that can both relieve symptoms and have minimal side effects is still ongoing to cover the large demographic affected by GERD. In the following review, analysis will be made of GERD, including possible regulatory activity, of certain drugs to the already discussed pathways involved in GERD patients.

Keywords: Antacids; GERD; H2-receptor antagonists; P-CABs; PPI.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work responsed in this paper.

Figures

Fig. 1
Fig. 1
Current status of different p-CABS drugs.
Fig. 2
Fig. 2
illustrates the prevalent complications and adverse reactions associated with prolonged PPI usage, along with the fundamental mechanisms responsible for each complication.
See this image and copyright information in PMC

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