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Clinical Trial
. 1979 Nov;28(5):365-7.
doi: 10.1097/00007890-197911000-00003.

Extended treatment with antithymocyte globulin (ATGAM) in renal allograft recipients

W J Wechter, R M Morrell, J Bergan, J C Rosenberg, J Turcotte, J R Schultz
Clinical Trial

Extended treatment with antithymocyte globulin (ATGAM) in renal allograft recipients

W J Wechter et al. Transplantation. 1979 Nov.

Abstract

Twenty renal allograft recipients were treated with antithymocyte globulin (ATGAM; ATG) for up to 16 weeks in addition to azathioprine and prednisone, while 20 controls received no ATG. The ATG group showed a lower incidence of first rejection episodes during the first month after transplantation, and also a better functional graft survival rate up to 2 years after transplantation. The results in this early ATG trial were better than those in subsequent trials which used 14-day treatment regimens. Longer treatment deserves another look.

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