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Case Reports
. 1985 May-Jun;13(3):134-6.
doi: 10.1007/BF01642873.

An amphotericin B-resistant case of rhinocerebral mucor mycosis

J Barnert, W Behr, H Reich
Case Reports

An amphotericin B-resistant case of rhinocerebral mucor mycosis

J Barnert et al. Infection. 1985 May-Jun.

Abstract

A 51-year-old male patient with diabetes mellitus complicated by ketoacidotic imbalance developed a rhinocerebral mucor mycosis that advanced despite early amphotericin B therapy and extensive surgical intervention. The MIC of amphotericin B for the isolated mucor species was 64 mg/l, meaning that in vitro resistance also existed. Only long-term treatment with ketoconazole (600 mg/day, perorally) was successful in curing the disease.

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