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Case Reports
. 1985 Sep;76(3):453-7.
doi: 10.1016/0091-6749(85)90726-2.

Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage

K G McGrath, B Zeffren, J Alexander, K Kaplan, R Patterson
Case Reports

Allergic reactions to streptokinase consistent with anaphylactic or antigen-antibody complex-mediated damage

K G McGrath et al. J Allergy Clin Immunol. 1985 Sep.

Abstract

Streptokinase used as a thrombolytic agent may produce immunologic drug reactions. We report a second case of IgE-mediated anaphylaxis and a late reaction to streptokinase. This late reaction was consistent with an IgG-mediated antigen-antibody disease with transient renal involvement, fever, and cutaneous lesions. The second case responded to prednisone therapy.

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