Is C-reactive protein sufficient to guide antimicrobial therapy for lower respiratory tract infections among children? Results from a stepped-wedge cluster randomized trial in Uganda
- PMID: 39288196
- PMCID: PMC11407648
- DOI: 10.1371/journal.pmed.1004467
Is C-reactive protein sufficient to guide antimicrobial therapy for lower respiratory tract infections among children? Results from a stepped-wedge cluster randomized trial in Uganda
Conflict of interest statement
CAR co-authored two of the publications cited in this Perspective. CAR was supported by the United States National Institutes of Health (K23HL173694). CAR has served as a research consultant to the World Health Organization, including for guidelines related to the management of lower respiratory tract infections. QB co-authored one of the publications cited in this Perspective. We declare no other conflict of interests.
References
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- Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021. Lancet Infect Dis. 2024;24(9):974–1002. Epub 20240415. doi: 10.1016/S1473-3099(24)00176-2 ; PubMed Central PMCID: PMC11339187. - DOI - PMC - PubMed
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- World Health Organization. Integrated Management of Childhood Illnesses (IMCI) chart booklet. 2014. p. 80.
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