Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024 Aug 21;15(9):1435-1436.
doi: 10.1021/acsmedchemlett.4c00408. eCollection 2024 Sep 12.

Novel Triazolopyridine Derivatives as DGAT2 Inhibitors for Treating Multiple Diseases

Ram W Sabnis  1
Affiliations
Editorial

Novel Triazolopyridine Derivatives as DGAT2 Inhibitors for Treating Multiple Diseases

Ram W Sabnis. ACS Med Chem Lett. .

Abstract

Provided herein are novel triazolopyridine derivatives as DGAT2 inhibitors, pharmaceutical compositions, use of such compounds in treating multiple diseases, and processes for preparing such compounds.

PubMed Disclaimer

Conflict of interest statement

The author declares no competing financial interest.

References

    1. Esler W. P.; Cohen D. E. Pharmacologic inhibition of lipogenesis for the treatment of NAFLD. J. Hepatol. 2024, 80, 362–377. 10.1016/j.jhep.2023.10.042. - DOI - PMC - PubMed
    1. Deng B.; Kong W.; Shen X.; Han C.; Zhao Z.; Chen S.; Zhou C.; Bae-Jump V. The role of DGAT1 and DGAT2 in regulating tumor cell growth and their potential clinical implications. J. Transl. Med. 2024, 22, 290. 10.1186/s12967-024-05084-z. - DOI - PMC - PubMed
    1. Huttasch M.; Roden M.; Kahl S. Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease?. Metabolism 2024, 157, 155937. 10.1016/j.metabol.2024.155937. - DOI - PubMed
    1. Wolk M.; Fedorova M. The lipid droplet lipidome. FEBS Lett. 2024, 598, 1215–1225. 10.1002/1873-3468.14874. - DOI - PubMed
    1. Sabnis R. W. Novel Imidazopyridine and Imidazopyridazine Derivatives as DGAT2 Inhibitors for Treating Multiple Diseases. ACS Med. Chem. Lett. 2024, 15, 1180–1181. 10.1021/acsmedchemlett.4c00286. - DOI - PMC - PubMed

Publication types

LinkOut - more resources