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Case Reports
. 2024 Aug 18;16(8):e67142.
doi: 10.7759/cureus.67142. eCollection 2024 Aug.

Stereotactic Ablative Radiation Therapy for Sacral Bone Metastasis in Recurrent Type A Thymoma: A Two-Year Follow-Up Demonstrating Pain Reduction and Local Control

Atsuto Katano  1 , Daichi Sugahara  1 , Ayane Yasui  2 , Yuki Nozawa  1 , Hideomi Yamashita  1
Affiliations
Case Reports

Stereotactic Ablative Radiation Therapy for Sacral Bone Metastasis in Recurrent Type A Thymoma: A Two-Year Follow-Up Demonstrating Pain Reduction and Local Control

Atsuto Katano et al. Cureus. .

Abstract

A 74-year-old Asian man presented with sacral bone metastasis-related pain caused by a metastatic thymoma. Computed tomography revealed an approximately 6-cm sacral mass, which was confirmed as a metastatic thymoma. The patient was referred to our department and underwent stereotactic ablative radiation therapy (SABR) using volumetric modulated arc therapy and received a total dose of 35 Gy in five fractions. One year after SABR, the sacral lesion had decreased in size, and the pain medication was reduced. After two years, the patient no longer required pain medication, indicating successful management of bone metastases in recurrent Type A Thymoma.

Keywords: pain; radiotherapy; recurrence; thymoma; thymus neoplasms.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Case of a 74-year-old man with sacral bone metastasis from thymoma
The yellow arrows indicated the sacral bone metastasis from thymoma. (A) A computed tomography scan showing a 3-cm mass in the sacral bone at the time of recurrence. (B) After three years of recurrence, the sacral lesion grew to approximately 6 cm. (C) Following stereotactic ablative radiotherapy (SABR), the sacral lesion reduced in size after one year, allowing for a decrease in pain medication. (D) Two years post-SABR, the sacral lesion further reduced in size, and the patient no longer required medication for sacral pain management.
Figure 2
Figure 2. Dose distribution of stereotactic ablative radiotherapy
Dose distribution of stereotactic ablative radiotherapy in the present case. The thin yellow line indicates the bladder and the thin blue line indicates the small bowel. The units for the numbers shown in the upper right label is centigray, which is one-hundredth (1%) of a gray.
See this image and copyright information in PMC

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