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Case Reports
. 2024 Aug 13:12:100422.
doi: 10.1016/j.ijregi.2024.100422. eCollection 2024 Sep.

Guillain-Barré syndrome in a 63-year-old patient possibly triggered by ehrlichiosis. Case report

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Case Reports

Guillain-Barré syndrome in a 63-year-old patient possibly triggered by ehrlichiosis. Case report

Carlos Mejía-Irías et al. IJID Reg. .

Abstract

Guillain-Barré syndrome is an immune-mediated acute demyelinating polyradiculoneuropathy, characterized by progressive flaccid weakness, triggered mainly by respiratory and gastrointestinal infections. We present the case of a 63-year-old male patient with a history of Ehrlichia infection, who consulted the internal medicine emergency department for lower back pain and progressive lower limb paresthesia, accompanied by decreased lower limb strength and nerve conduction velocity test, with results compatible with acute demyelinating sensorimotor polyradiculoneuropathy. To the best of our knowledge, this is the first documented case in Honduran medical literature; in our research, no other cases were found in Latin America or Europe. The importance of the topic and its dissemination in countries where Ehrlichia infection exists is that when cases of Guillain-Barré syndrome that cannot be associated with previous gastrointestinal or respiratory infection, they could be attributed to Ehrlichia infection as a possible cause; therefore, exhaustive preventive measures can be established regarding the transmitting vector of ehrlichiosis.

Keywords: Acute autoimmune neuropathy; Ehrlichiosis; Guillain–Barré syndrome.

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Conflict of interest statement

The authors have no competing interests to declare.

References

    1. Malhis JR, Mahmoud A, Belote A, Ebers A. Case of ehrlichiosis induced Guillain-Barre Syndrome in a 71 year-old female. IDCases. 2021;26:e01301. doi: 10.1016/j.idcr.2021.e01301. - DOI - PMC - PubMed
    1. Ramírez Izcoa A, Izaguirre González AI, Cerna Lizardo J, Hernandez Bustillo G, Cordova Tello D. Síndrome de Guillain Barré en paciente pediátrico: diagnóstico y rehabilitación. Reporte de caso. Rev Med Hondur. 2016;84:118–122.
    1. Chandrashekhar S, Dimachkie MM. Guillain-Barré syndrome in adults: pathogenesis, clinical features, and diagnosis. In: Date SJM, Rabinstein AA, editors. UpToDate [Internet]. July 2024 [cited 2024 Mar 10]. Available from: https://www.uptodate.com/contents/guillain-barre-syndrome-in-adults-path....
    1. Bragazzi NL, Kolahi A-A, Nejadghaderi SA, Lochner P, Brigo F, Naldi A, et al. Global, regional, and national burden of Guillain–Barré syndrome and its underlying causes from 1990 to 2019. J Neuroinflammation. 2021;18:264. doi: 10.1186/s12974-021-02319-4. - DOI - PMC - PubMed
    1. Finsterer J. Triggers of Guillain–Barré syndrome: Campylobacter jejuni predominates. Int J Mol Sci. 2022;23:14222. doi: 10.3390/ijms232214222. - DOI - PMC - PubMed

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