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Case Reports
. 1985 Aug;60(8):774-6.
doi: 10.1136/adc.60.8.774.

Pathogenesis of liver damage during parenteral nutrition: is lipofuscin a clue?

H M Berger, A L Den Ouden, J J Calame
Case Reports

Pathogenesis of liver damage during parenteral nutrition: is lipofuscin a clue?

H M Berger et al. Arch Dis Child. 1985 Aug.

Abstract

Lipofuscin develops in cells when peroxidation damage occurs. Its development in the liver of patients receiving prolonged parenteral nutrition suggests that peroxidation damage by free radicals has occurred. Deficiencies in antioxidants such as vitamin E may be an important contributing factor.

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