The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19

Francesco Scavello¹, Enrico Brunetta², Sarah N Mapelli¹, Emanuele Nappi³, Ian David García Martín⁴, Marina Sironi¹, Roberto Leone¹, Simone Solano¹, Giovanni Angelotti⁵, Domenico Supino¹, Silvia Carnevale¹, Hang Zhong³, Elena Magrini¹, Matteo Stravalaci¹, Alessandro Protti⁶, Alessandro Santini⁶, Elena Costantini⁷, Victor Savevski⁵, Antonio Voza⁸, Barbara Bottazzi¹, Michele Bartoletti⁹, Maurizio Cecconi⁶, Alberto Mantovani¹⁰, Paola Morelli², Federica Tordato², Cecilia Garlanda¹¹; Humanitas Covid-19 task force¹

Affiliations

¹ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
² Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
³ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy.
⁴ Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy.
⁵ Artificial Intelligence Center, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁶ Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁷ Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁸ Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Emergency Department, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁹ Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy.
¹⁰ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; The William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
¹¹ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy. Electronic address: cecilia.garlanda@humanitasresearch.it.

PMID: 39299004
PMCID: PMC11424927
DOI: 10.1016/j.ebiom.2024.105372

Published Erratum

The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19

Francesco Scavello et al. EBioMedicine. 2024 Oct.

. 2024 Oct:108:105372.

doi: 10.1016/j.ebiom.2024.105372. Epub 2024 Sep 18.

Authors

Affiliations

¹ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
² Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy.
³ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy.
⁴ Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy.
⁵ Artificial Intelligence Center, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁶ Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁷ Department of Anesthesia and Intensive Care, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁸ Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; Emergency Department, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.
⁹ Infectious Diseases Unit, Hospital Health Direction, IRCCS Humanitas Research Hospital, 20089 Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy.
¹⁰ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy; The William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
¹¹ IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Milan, Italy. Electronic address: cecilia.garlanda@humanitasresearch.it.

PMID: 39299004
PMCID: PMC11424927
DOI: 10.1016/j.ebiom.2024.105372

No abstract available

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Erratum for

The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19.
Scavello F, Brunetta E, Mapelli SN, Nappi E, García Martín ID, Sironi M, Leone R, Solano S, Angelotti G, Supino D, Carnevale S, Zhong H, Magrini E, Stravalaci M, Protti A, Santini A, Costantini E, Savevski V, Voza A, Bottazzi B, Bartoletti M, Cecconi M, Mantovani A, Morelli P, Tordato F, Garlanda C. Scavello F, et al. EBioMedicine. 2024 Jul;105:105213. doi: 10.1016/j.ebiom.2024.105213. Epub 2024 Jun 21. EBioMedicine. 2024. PMID: 38908098 Free PMC article.

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The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19

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The long Pentraxin PTX3 serves as an early predictive biomarker of co-infections in COVID-19

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