Brown algae biomass for fucoxanthin, fucoidan and alginate; update review on structure, biosynthesis, biological activities and extraction valorisation

Abstract

Natural compounds promoting human health are the main focus of research nowadays. Fucoxanthin, fucoidan and alginate are such bioactive compounds that are extracted from marine brown algae. Extracting these 3 compounds through successive extraction enhances the commercial value of the brown algae biomass. There are studies on successive extraction of fucoidan and alginate but not with fucoxanthin which displays various biological bioactivities. Alginate, a polysaccharide presents 45 % in the cell wall of brown algae. Fucoidan, a sulphated polysaccharide proved showing various bioactivities. These bioproducts yield are vary depending on the species. Dictyota species recorded high fucoxanthin content of 7 %. Ascophyllum nodosum was found with high fucoidan of 16.08 % by direct extraction. Maximum alginate of 45.79 % was recorded from the brown alga Sargassum cymosum and by successive extraction 44 % was recorded from Ecklonia radiata. Fucoxanthin exits in two isomers as trans and cis forms. Based on linkage, fucoidan structure is found in 3 forms as 1,3- or 1,4- or alternating 1,3- and 1,4-linked fucose in the polysaccharide residues. Fucoidan composition varys depending on the degree of sulphation, composition of monosaccharides and location of collection. In alginate, its property relies on the mannuronic acid and guluronic acid composition. Biosynthesis of these 3 compounds is not much explored. Keeping this view which signify sequential extraction towards biomass valorisation, fucoxanthin, fucoidan and alginate extracted from the brown algae species focusing yield, extraction, characterisation, biosynthesis and biological activities were compiled and critically analysed and discussed in this review.

Keywords: Alginate; Biorefinery; Brown algae biomass; Fucoidan; Fucoxanthin; Sequential extraction; Valorisation.