[Phorbol diester induces phenotypic and functional changes in human T-lymphocyte clones]
[Article in
French]
- PMID: 3930011
Item in Clipboard
[Phorbol diester induces phenotypic and functional changes in human T-lymphocyte clones]
[Article in
French]
C R Acad Sci III.
1985.
Abstract
Tumor promoting phorbol myristate acetate (PMA) induce to enhance the expression of IL2 Receptor and to decrease the antigen receptor expression on the cell surface. The same phenotypic changes are also observed when the T cell clones are stimulated by the specific ligand. In contrast to the IL2 Receptor induced by the specific antigen, the ones induced by PMA are less active.