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. 2024 Sep 1;1(9):422-424.
doi: 10.5588/ijtldopen.24.0124. eCollection 2024 Sep.

Cartridge-based sequencing for bedaquiline resistance detection from sputum

J D Limberis  1 , R J Nagel  2 , D Block  2 , R E Colman  3 , A Nalyvayko  2 , Z Howard  4 , S Dewell  2 , S Chakravorty  2 , J Z Metcalfe  1
Affiliations

Cartridge-based sequencing for bedaquiline resistance detection from sputum

J D Limberis et al. IJTLD Open. .
No abstract available

Keywords: Xpert Ultra; atpE; bedaquiline; drug-resistant tuberculosis; rv0678; targeted next-generation sequencing; tuberculosis.

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Conflict of interest statement

Conflicts of interest: RJN, DB, SD, and SC are Cepheid employees. All other authors have no conflicts of interest.

References

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    1. Zürcher K, et al. . Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multicentre cohort study. Lancet Infect Dis. 2019;19(3):298–307. - PMC - PubMed
    1. WHO 2023 . Use of targeted next-generation sequencing to detect drug-resistant tuberculosis. Geneva, Switzerland: WHO, 2023.
    1. Ali N, et al. . Current nucleic acid extraction methods and their implications to point-of-care diagnostics. Biomed Res Int. 2017;2017:9306564. - PMC - PubMed