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. 2025 Jun;26(4):541-560.
doi: 10.1007/s10198-024-01716-9. Epub 2024 Sep 20.

Does implementing opt-out solve the organ shortage problem? Evidence from a synthetic control approach

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Does implementing opt-out solve the organ shortage problem? Evidence from a synthetic control approach

Selina Schulze Spuentrup. Eur J Health Econ. 2025 Jun.

Abstract

In light of the persistent shortage of organ donations needed to save precious human lives, several countries have modified their organ donation laws by introducing an opt-out system, making every deceased a potential organ donor unless the person has objected. This study examines the impact of adopting opt-out on organ donation rates. Using a panel dataset covering a 21-year period, I apply a synthetic control approach to focus on countries that changed their prevailing organ donation legislation from opt-in to opt-out. I compare them to a synthetic counterfactual from countries that have kept their legislation the same since 1999. Synthetic control estimates show that Argentina and Wales achieved substantially higher organ donation rates with the shift from an opt-in to an opt-out system than without the reform taking place. My findings suggest that as one strategy among others, implementing opt-out cannot solve the organ shortage problem entirely but effectively contributes to reducing it considerably.

Keywords: Informed consent; Opt-in; Opt-out; Organ donation; Presumed consent; Synthetic control method.

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Conflict of interest statement

Declarations. Conflict of interest: The author has no conflict of interest to declare that are relevant to the content of this article.

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