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. 1985;28(5):607-9.
doi: 10.1007/BF00544075.

Evidence for a GABAergic control of the exercise-induced rise in GH in man

L Steardo, M Iovino, P Monteleone, M Agrusta, F Orio

Evidence for a GABAergic control of the exercise-induced rise in GH in man

L Steardo et al. Eur J Clin Pharmacol. 1985.

Abstract

The effect of the GABAergic drug sodium valproate (SV) on the exercise-induced release of growth hormone (GH) was investigated in 10 healthy males. The exercise test consisted of using a stationary bicycle ergometer at 450 kg/min for 20 min. SV 600 mg blunted the increase in GH induced by the exercise, suggesting GABAergic regulation of GH secretion in man, at least under certain physiological conditions.

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