Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2024 Aug 1;27(8):407-413.
doi: 10.34172/aim.31072. Epub 2024 Aug 1.

Pattern of Participation in Colorectal Cancer Screening from a Population-Based Screening Program in Iran

Farimah Rahimi  1 , Reza Rezayatmand  1 , Elaheh Najafi  2 , Zahra Ravankhah  3 , Elham Tabesh  4 , Peyman Adibi  4
Affiliations
Observational Study

Pattern of Participation in Colorectal Cancer Screening from a Population-Based Screening Program in Iran

Farimah Rahimi et al. Arch Iran Med. .

Abstract

Background: In Isfahan, the fecal immunochemical test (FIT) has been used since January 2016 as part of the Iran's Package of Essential Non-communicable Diseases (IraPEN) program for colorectal cancer (CRC) screening. The test is recommended for people who are 50-70 years old. Then, those with positive results would be referred for colonoscopy. This study aims to describe the uptake of the program and its outcome.

Methods: A retrospective observational study was performed by collecting data from Isfahan Vice-Chancellor for Health database for this study purpose. The number of participators, the number of positive FIT, and the number of detected polyps or cancers were determined.

Results: Between 2016 and 2019, the number of participants in the program reached 345 207 individuals (nearly 40% of the eligible population of 874 674). Totally, 21 264 participants (6.1%) had positive tests, of whom about 20% underwent the recommended colonoscopy with available reports, and 971 (24%) and 110 (3%) patients were diagnosed with polyps and CRC, respectively.

Conclusion: Over four years of screening with FIT in Isfahan, 40% of the eligible population participated. Among those with positive FIT results, 20% underwent colonoscopy, and approximately 26% of these individuals were identified as having polyps or cancer. This study provides valuable insights into the uptake and outcomes of a population-based CRC screening program in Isfahan, Iran. The findings highlight the need for targeted interventions to increase participation rates and improve the detection of polyps and CRC cases.

Keywords: Colorectal cancer screening; Fecal immunochemical test; Iran; Isfahan; Participation rate.

PubMed Disclaimer

Conflict of interest statement

Competing Interests

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Figure 2
Figure 2
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Xi Y, Xu P. Global colorectal cancer burden in 2020 and projections to 2040. Transl Oncol. 2021;14(10):101174. doi: 10.1016/j.tranon.2021.101174. - DOI - PMC - PubMed
    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. doi: 10.3322/caac.21660. - DOI - PubMed
    1. Green BB, Coronado GD. “BeneFITs” to increase colorectal cancer screening in priority populations. JAMA Intern Med. 2014;174(8):1242–3. doi: 10.1001/jamainternmed.2014.730. - DOI - PMC - PubMed
    1. Hoseini B, Rahmatinejad Z, Goshayeshi L, Bergquist R, Golabpour A, Ghaffarzadegan K, et al. Colorectal cancer in north-eastern Iran: a retrospective, comparative study of early-onset and late-onset cases based on data from the Iranian hereditary colorectal cancer registry. BMC Cancer. 2022;22(1):48. doi: 10.1186/s12885-021-09132-5. - DOI - PMC - PubMed
    1. Iran, Islamic Republic of, Both Sexes, All Ages. International Agency for Research on Cancer - World Health Organization. https://gco.iarc.fr/today/online-analysis-table?v=2020&mode=cancer&mode_.... Published 2020.

Publication types