Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2024 May 16;24(4):286-288.
doi: 10.1177/15357597241253683. eCollection 2024 Jul-Aug.

A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability

Affiliations
Comment

A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability

Ania K Dabrowski et al. Epilepsy Curr. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Comment on

  • LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.
    Libé-Philippot B, Lejeune A, Wierda K, Louros N, Erkol E, Vlaeminck I, Beckers S, Gaspariunaite V, Bilheu A, Konstantoulea K, Nyitrai H, De Vleeschouwer M, Vennekens KM, Vidal N, Bird TW, Soto DC, Jaspers T, Dewilde M, Dennis MY, Rousseau F, Comoletti D, Schymkowitz J, Theys T, de Wit J, Vanderhaeghen P. Libé-Philippot B, et al. Cell. 2023 Dec 21;186(26):5766-5783.e25. doi: 10.1016/j.cell.2023.11.028. Cell. 2023. PMID: 38134874 Free PMC article.

References

    1. Libé-Philippot B, Lejeune A, Wierda K, et al. LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons. Cell. 2023;186(26):5766–5783.e25. doi:10.1016/j.cell.2023.11.028 - PMC - PubMed
    1. Suzuki IK, Gacquer D, Van Heurck R, et al. Human-specific NOTCH2NL genes expand cortical neurogenesis through delta/notch regulation. Cell. 2018;173(6):1370–1384.e16. - PMC - PubMed
    1. Mohan H, Verhoog MB, Doreswamy KK, et al. Dendritic and axonal architecture of individual pyramidal neurons across layers of adult human neocortex. Cereb Cortex. 2015;25(12):4839–4853. - PMC - PubMed
    1. Deitcher Y, Eyal G, Kanari L, et al. Comprehensive morpho-electrotonic analysis shows 2 distinct classes of L2 and L3 pyramidal neurons in human temporal cortex. Cereb Cortex. 2017;27(11):5398–5414. - PMC - PubMed
    1. Yáñez IB, Muñoz A, Contreras J, Gonzalez J, Rodriguez-Veiga E, DeFelipe J. Double bouquet cell in the human cerebral cortex and a comparison with other mammals. J Comp Neurol. 2005;486(4):344–360. - PubMed

LinkOut - more resources