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Case Reports
. 2024 Sep 9;11(4):100146.
doi: 10.1016/j.acpath.2024.100146. eCollection 2024 Oct-Dec.

Educational Case: Acetaminophen hepatotoxicity: Pathophysiology and evaluation of acute liver failure

Hunter L Monroe  1 , Tony El Jabbour  1
Affiliations
Case Reports

Educational Case: Acetaminophen hepatotoxicity: Pathophysiology and evaluation of acute liver failure

Hunter L Monroe et al. Acad Pathol. .
No abstract available

Keywords: Acetaminophen; Acute liver failure; Hepatobiliary; Liver toxins; Organ system pathology; Pathology competencies.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
H&E-stained sections obtained from transjugular liver biopsy. A. Centrilobular (zone 3) necrosis is characterized by hepatocyte dropout surrounding a central vein (black arrow) with intervening congestion and mild lymphoplasmacytic infiltrates. Note the absence of viable hepatocytes (20×). B. Periportal (zone 1) liver parenchyma is preserved with portal vein (orange arrow) and intact hepatocytes (green arrow) shown (20×).
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