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Case Reports
. 2024 Sep 23;18(9):e01851.
doi: 10.1213/XAA.0000000000001851. eCollection 2024 Sep 1.

In-Home Intravenous Dexmedetomidine Infusion for Treatment of Dystonia: A Pediatric Case Report

Gwendolyn J Richner  1   2 , Stephanie S Allen  1 , Lindsay M Adair  3 , Daniel H Grossoehme  1   2 , Catherine A Kelly-Langen  1 , Wendy J McNair  1 , Madelyne L Williams  1 , Sarah Friebert  1   2
Affiliations
Case Reports

In-Home Intravenous Dexmedetomidine Infusion for Treatment of Dystonia: A Pediatric Case Report

Gwendolyn J Richner et al. A A Pract. .

Abstract

The off-label use of an intravenous dexmedetomidine infusion is an option for refractory symptoms in pediatric palliative care with a few published cases of in-home use, most limited to end-of-life care. After an intrathecal baclofen pump malfunction with meningitis and medication withdrawal, a 17-year-old adolescent with quadriparetic cerebral palsy and paroxysmal autonomic instability experienced relief of refractory pain and dystonia with an in-home intravenous dexmedetomidine infusion. His interdisciplinary care team collaborated to establish safety measures and adjust his home medication regimen to further improve quality of life well before his end of life.

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Conflict of interest statement

The authors declare no conflicts of interest.

References

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