Incriminating leishmaniases vectors in Colombia: An overview and roadmap for future research

Abstract

A major challenge in defining the vector status of phlebotomine sand flies is selecting the appropriate criteria. Vectors can be graded by importance, with successful transmission as the highest grade. Potential vectors are often identified based on high frequency in transmission foci, anthropophily, and more recently by identification of DNA in field samples. However, a species' ability to transmit a pathogen depends not only on its intrinsic biology of sand fly-Leishmania interactions but also on ecological parameters, which are rarely evaluated. This study aimed to analyze the literature data describing characteristics of Colombian sand flies related to their role as vectors of Leishmaniinae parasites. Based on information contained in scientific publications using combinations of five criteria, sand fly species were graded into five levels, and 26 species were considered as potential or proven leishmaniasis vectors in Colombia. Levels one to four refer to potential or suspected status, while level five denotes proven vectors. Studying vectors in a regional context is crucial because species' behaviors vary with environmental and ecological conditions, meaning a species may be a key vector in one area but not in another. A better understanding of vector-parasite interactions will aid in developing innovative control strategies and formulating significant epidemiological perspectives.

Keywords: Colombia; Leishmaniases; Sand fly vectors; Vectorial capacity.