Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Oct;73(5):401-5.
doi: 10.1080/00034983.1979.11687279.

The concentration of chloroquine in serum during short and long term malaria prophylaxis with standard and 'double' dosage in non-immunes: clinical implications

J Brohult, L Rombo, V Sirleaf, E Bengtsson

The concentration of chloroquine in serum during short and long term malaria prophylaxis with standard and 'double' dosage in non-immunes: clinical implications

J Brohult et al. Ann Trop Med Parasitol. 1979 Oct.

Abstract

The concentration of chloroquine in serum was analysed after one week, six weeks and one year on standard dose prophylaxis (300 mg chloroquine base once a week) and after six months on the double dose. After six weeks, the standard dose gave adequate protection against malaria. During the first weeks of prophylaxis insufficient protection might be achieved by the customary standard dose. In a double-dose group many values reached the point above which a higher incidence of side-reactions have been observed.

PubMed Disclaimer