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. 2024 Sep 19:17:3499-3508.
doi: 10.2147/DMSO.S484616. eCollection 2024.

Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study

Mingyue Shang #  1 , Zhehong Li #  1 , Dexiao Du #  1 , Guangzhong Xu  1 , Dongbo Lian  1 , Zhaohui Liao  1 , Dezhong Wang  1 , Buhe Amin  1 , Zheng Wang  1 , Weijian Chen  1 , Nengwei Zhang  1 , Liang Wang  1
Affiliations

Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study

Mingyue Shang et al. Diabetes Metab Syndr Obes. .

Abstract

Purpose: Obesity and related complications are managed by One Anastomosis Gastric Bypass (OAGB) and Single Anastomosis Duodeno-Jejunal Bypass with Sleeve Gastrectomy (SADJB-SG), both of which are adapted from traditional gastric bypass procedures. However, there are no current comparative studies on the safety and efficacy of these two surgical procedures.

Patients and methods: Preoperative baseline data of patients who had undergone OAGB and SADJB-SG surgeries from June 2019 to June 2021 were retrospectively analyzed at our bariatric facility. Postoperative data, including weight changes, improvement in type 2 diabetes (T2DM), and complication rates were collected over 2 years. This was followed by a comprehensive evaluation of the safety and efficacy of the two surgical procedures.

Results: A total of 63 patients completed the follow-up in this study. At the 24-month follow-up, excess weight loss percentage (EWL%) for the OAGB and SADJB-SG was 73.970±5.005 and 75.652±7.953, respectively (P-value = 0.310); total weight loss percentage (TWL%) was 24.006±8.231 and 23.171±6.600, respectively (P-value = 0.665). The diabetes remission rates for the two groups were 71.429% and 69.048%, respectively (P-value = 0.846). The cost for OAGB was 55088.208±1508.220 yuan, which was significantly lower than the 57538.195±1374.994 yuan for SADJB-SG (P-value< 0.001).

Conclusion: The two surgical procedures are reliable in terms of safety and efficacy, and each has distinct advantages. While OAGB has reduced operational expenses, SADJB-SG offers a broader range of applicability.

Keywords: efficacy; one anastomosis gastric bypass; safety; single anastomosis duodeno-jejunal bypass with sleeve gastrectomy.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
EWL% dynamics trends up to 24 months postoperatively in two groups.
Figure 2
Figure 2
TWL% dynamics trends up to 24 months postoperatively in two groups.
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