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. 2025 Jan;24(1):e16583.
doi: 10.1111/jocd.16583. Epub 2024 Sep 25.

Combined Forehead and Temporal Lifting: An Innovative Approach to Lanluma V Treatment

Larry Wu  1 , Giovanni Salti  2
Affiliations

Combined Forehead and Temporal Lifting: An Innovative Approach to Lanluma V Treatment

Larry Wu et al. J Cosmet Dermatol. 2025 Jan.

Abstract

Background: Excess skin laxity over the upper face can contribute to aging over the mid and lower face. We describe an innovative nonsurgical technique of facial rejuvenation by injecting Lanluma V over the scalp's vertex and parietal regions. Lanluma V is a poly-l-lactic acid (PLLA)-based collagen stimulator which contains 210 mg of PLLA, distributed by Sinclair Pharmaceutical. Lanluma V works by stimulating collagen regeneration to provide support for the treated area.

Method: A retrospective review of 12 consecutive patients treated with Lanluma V over the vertex and parietal regions of the scalp to achieve nonsurgical rejuvenation of the upper, middle, and lower thirds of the face was conducted. The patients were treated over two sessions, 1 month apart. The treated patients were reviewed by a plastic surgeon and rated under the Global Aesthetic Improvement Scale (GAIS) 6 months after treatment.

Results: The patients achieved an overall average of 1.16 grade improvement in GAIS. The average follow-up period is 6 months following completion of treatment. There was no reported incidence of non-scarring alopecia, which has been reported in the use of other, more viscous fillers such as calcium hydroxyapatite or high G' hyaluronic acid.

Conclusion: This innovative method of combined forehead and temporal lifting with Lanluma V allows for an average 1.16 grade improvement in GAIS. There is no reported incidence of non-scarring alopecia, which has been associated with other fillers.

Keywords: Global Aesthetic Improvement Scale; Lanluma V; forehead lift; nonsurgical facial rejuvenation; non‐scarring alopecia; poly‐l‐lactic acid; temporal lift.

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Conflict of interest statement

Larry Wu: none; Giovanni Salti: Consultant to Sinclair pharmaceutical.

Figures

FIGURE 1
FIGURE 1
Black dots showing the entry points for treatment over the vertex and the parietal region. White arrows showing the direction of forehead and temporal lifting following regeneration of collagen.
FIGURE 2
FIGURE 2
Quantificare diagram showing before and after, 11 months following treatment. Yellow arrows over the temporal area showing the temporal lift following treatment. Red arrows over the forehead demonstrating direction of forehead lift following treatment.
FIGURE 3
FIGURE 3
Picture showing before and after following treatment. The forehead and lower face contours have improved following treatment with combined forehead and temporal lift with Lanluma V.
FIGURE 4
FIGURE 4
Six‐month later ultrasound picture showing layer where Lanluma V was injected over the galea.
See this image and copyright information in PMC

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