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. 2024 Oct;30(10):2199-2202.
doi: 10.3201/eid3010.240609.

Respiratory Syncytial Virus Prevalence and Risk Factors among Healthy Term Infants, United States

Ferdinand Cacho, Tebeb Gebretsadik, Larry J Anderson, James D Chappell, Christian Rosas-Salazar, Justin R Ortiz, Tina Hartert

Respiratory Syncytial Virus Prevalence and Risk Factors among Healthy Term Infants, United States

Ferdinand Cacho et al. Emerg Infect Dis. 2024 Oct.

Abstract

In a population-based birth cohort study of respiratory syncytial virus surveillance in the United States, 897/1,680 (53.4%) children were infected during infancy; 25 (2.8%) of those were hospitalized. Among symptomatic infants, 143/324 (44.1%) had lower respiratory tract infections. These data provide benchmarks to monitor effects of maternal vaccines and extended half-life monoclonal antibodies.

Keywords: RSV; United States; infant; respiratory infections; respiratory syncytial virus; risk factors; viruses.

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Figures

Figure 1
Figure 1
Percentages of RSV infection, symptomatic disease, LRTI, and URTI in the first year of life among healthy term infants, United States. Each ring represents the subset of the inner ring and adds to 100%. LRTI, lower respiratory tract infection; RSV, respiratory syncytial virus; URTI, upper respiratory tract infections.
Figure 2
Figure 2
Respiratory syncytial virus infection risk factors in the first year of life in study of RSV among healthy term infants, United States. Adjusted odds ratios were estimated using multivariable logistic regression, referent is October birth month. Dots indicate odds ratio and horizontal line 95% CI. Dashed vertical line indicates the null effect. Asterisk indicates residence in a census tract with increasing percentage of people below the poverty level (interquartile range difference).
See this image and copyright information in PMC

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