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. 2024 Oct;30(10):2174-2177.
doi: 10.3201/eid3010.240917.

Chlorine Inactivation of Elizabethkingia spp. in Water

David A Holcomb, Diana Riner, Benjamin Cowan, Zainab Salah, Wiley C Jennings, Mia C Mattioli, Jennifer L Murphy

Chlorine Inactivation of Elizabethkingia spp. in Water

David A Holcomb et al. Emerg Infect Dis. 2024 Oct.

Abstract

We performed chlorine inactivation experiments for Elizabethkingia anophelis and E. meningoseptica bacterial strains from clinical and environmental sources. Free chlorine concentration × contact time values <0.04 mg·min/L achieved 99.9% inactivation of Elizabethkingia species, indicating chlorine susceptibility. Measures to control biofilm producing pathogens in plumbing are needed to prevent Elizabethkingia bacterial infections.

Keywords: Disinfection; Drug Resistance; Elizabethkingia; Flavobacteriaceae; antimicrobial resistance; bacteria; biofilms; chlorine; disease outbreaks; environmental microbiology; halogenation; opportunistic infections; sanitation; water; water supply.

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Figures

Figure
Figure
Observed and model-predicted log10 inactivation in study of chlorine inactivation of Elizabethkingia spp. in water. Samples from environmental and clinical sources were exposed to chlorine in water with increasing contact time at an initial dose of 0.2 mg/L FCR. Panels show comparisons in modeled inactivation by model specification. A) All data used for both models. B) Stratified by species, Chick-Watson model. C) Strain source, Chick-Watson model. Curved lines indicate model-predicted inactivation; dots, observed inactivation; and shaded regions, model 95% prediction intervals. FCR, free chlorine residual.
See this image and copyright information in PMC

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