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. 2024 Sep 25;54(12):1-2.
doi: 10.1017/S0033291724002071. Online ahead of print.

Letter to the editor regarding 'Is combined antidepressant medication (ADM) and psychotherapy better than either monotherapy at preventing suicide attempts and other psychiatric serious adverse events for depressed patients? A rare events meta-analysis'

Affiliations

Letter to the editor regarding 'Is combined antidepressant medication (ADM) and psychotherapy better than either monotherapy at preventing suicide attempts and other psychiatric serious adverse events for depressed patients? A rare events meta-analysis'

Alexander Lisinski et al. Psychol Med. .
No abstract available

Keywords: antidepressants; combined treatment; depression; major depressive disorder; meta-analysis; pharmacology; psychiatry; psychoterapy.

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Figures

Figure 1.
Figure 1.
Forest plot for treatment effect comparing combined treatment with antidepressants and placebo to psychotherapy-only, using corrected numbers of events. Events refer to the number of patient(s) within a specific treatment arm that had a negative treatment outcome (i.e. suicide attempt, psychiatric emergency department visit, psychiatric hospitalization, and/or suicide death). ADM, antidepressant medication; CI, confidence interval; FE, fixed effects; PSY, psychotherapy.

References

    1. Healy, D., & Whitaker, C. (2003). Antidepressants and suicide: Risk-benefit conundrums. Journal of Psychiatry and Neuroscience, 28(5), 331–337. https://www.ncbi.nlm.nih.gov/pubmed/14517576 - PMC - PubMed
    1. Hieronymus, F., Lisinski, A., Näslund, J., & Eriksson, E. (2018). Katakam and co-workers have not shown SSRIs to be harmful and ineffective and should stop claiming that they have. Acta Neuropsychiatrica, 30(5), 266–274. 10.1017/neu.2018.15 - DOI - PubMed
    1. Huijbers, M. J., Spinhoven, P., Spijker, J., Ruhe, H. G., van Schaik, D. J., van Oppen, P., … Speckens, A. E. (2015). Adding mindfulness-based cognitive therapy to maintenance antidepressant medication for prevention of relapse/recurrence in major depressive disorder: Randomised controlled trial. Journal of Affective Disorders, 187, 54–61. 10.1016/j.jad.2015.08.023 - DOI - PubMed
    1. Huijbers, M. J., Spinhoven, P., Spijker, J., Ruhe, H. G., van Schaik, D. J., van Oppen, P., … Speckens, A. E. (2016). Discontinuation of antidepressant medication after mindfulness-based cognitive therapy for recurrent depression: Randomised controlled non-inferiority trial. British Journal of Psychiatry, 208(4), 366–373. 10.1192/bjp.bp.115.168971 - DOI - PMC - PubMed
    1. Klatte, R., Strauss, B., Fluckiger, C., & Rosendahl, J. (2023). Adverse events in psychotherapy randomized controlled trials: A systematic review. Psychotherapy Research, 13(1), 1–16. 10.1080/10503307.2023.2286992 - DOI - PubMed

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