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. 2024 Sep 25;166(1):380.
doi: 10.1007/s00701-024-06282-w.

Complication rates after autologous cranioplasty following decompressive craniectomy

Leonard Ritter  1 , Kilian Strohhäcker  2 , Karl-Michael Schebesch  2 , Thomas Eibl  2 , Julius Höhne  2 , Adrian Liebert  2
Affiliations

Complication rates after autologous cranioplasty following decompressive craniectomy

Leonard Ritter et al. Acta Neurochir (Wien). .

Abstract

Objective: The reimplantation of autologous bone grafts after decompressive craniectomy (DC) is still up for debate. The objective of this study was to analyze the surgical revision rate for autologous cranioplasties in our center, aiming to identify predictors for procedure-related-complications.

Methods: A retrospective single-center study was conducted for adult patients who underwent autologous cranioplasty after DC. The primary endpoint was the complication rate in terms of surgical revision and removal of the bone graft: infection, new onset seizures, dislocation, haemorrhage, osteolysis, wound dehiscence and cerebrospinal fluid (CSF) fistula. Demographic data, medical records, surgical reports and imaging studies were analysed and risk factors for complications were evaluated.

Results: 169 consecutive patients were included. The median interval between DC and cranioplasty was 84 days. Mean age was 51 ± 12.4 years. 26 patients (15.3%) had revision surgery for following reasons. n = 9 implant dislocations (5.3%), n = 7 osteolysis (3.6%), n = 6 infections (3.6%), n = 5 had re-bleedings (3%), n = 5 wound dehiscences (3%), and n = 2 CSF fistulas (1.2%). 18 patients developed new seizures (10.7%). Bi- and multivariate analysis revealed three independent risk factors, simultaneous ventriculo-peritoneal (VP) shunting increased the risk for material dislocation (p < 0.001); large bone grafts (> 193.5 cm2) increased the risk for osteolysis (p = 0.001) and bifrontal cranioplasties were associated with higher risk for infections (p = 0.04).

Conclusion: The complication rates in our study were comparable to previously reported data for autologous or artificial cranioplasties. As osteolysis was correlated to larger bone grafts, a synthetic alternative should be considered in selected cases.

Keywords: Autologous cranioplasty; Bone flap resorption; Complications; Cranial defect; Decompressive craniectomy; Infection; Risk factors; Skull reconstruction.

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Conflict of interest statement

The authors have no competing interests to declare that are relevant to the content of this article.

Figures

Fig. 1
Fig. 1
Preoperative and postoperative CT scan of a patient receiving an autologous cranioplasty
See this image and copyright information in PMC

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