Activation of c-Ki-ras gene in human pancreatic cancer
- PMID: 3932275
Activation of c-Ki-ras gene in human pancreatic cancer
Abstract
DNA isolated from a lymph node with metastasis from pancreatic adenocarcinoma in a Japanese male patient transformed NIH3T3 cells upon transfection by the calcium-phosphate precipitation technique. Analysis of DNA from the transformant revealed the presence of an activated human c-Ki-ras gene, which is considered to be responsible for the transformation of the NIH3T3 cells.
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