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. 1985 Sep;76(9):792-5.

Activation of c-Ki-ras gene in human pancreatic cancer

V S Prassolov, H Sakamoto, S Nishimura, M Terada, T Sugimura
  • PMID: 3932275

Activation of c-Ki-ras gene in human pancreatic cancer

V S Prassolov et al. Jpn J Cancer Res. 1985 Sep.

Abstract

DNA isolated from a lymph node with metastasis from pancreatic adenocarcinoma in a Japanese male patient transformed NIH3T3 cells upon transfection by the calcium-phosphate precipitation technique. Analysis of DNA from the transformant revealed the presence of an activated human c-Ki-ras gene, which is considered to be responsible for the transformation of the NIH3T3 cells.

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