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Comment
. 2024 Sep 27;385(6716):1418-1420.
doi: 10.1126/science.ads2152. Epub 2024 Sep 26.

Microbial hoolIgAn dismantles gut defenses

Emma Slack  1   2   3
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Comment

Microbial hoolIgAn dismantles gut defenses

Emma Slack. Science. .

Abstract

Immunoglobulin degradation by a gut bacterium causes immunodeficiency in mice.

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  • A host-adapted auxotrophic gut symbiont induces mucosal immunodeficiency.
    Lu Q, Hitch TCA, Zhou JY, Dwidar M, Sangwan N, Lawrence D, Nolan LS, Espenschied ST, Newhall KP, Han Y, Karell PE, Salazar V, Baldridge MT, Clavel T, Stappenbeck TS. Lu Q, et al. Science. 2024 Sep 27;385(6716):eadk2536. doi: 10.1126/science.adk2536. Epub 2024 Sep 27. Science. 2024. PMID: 39325906 Free PMC article.

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