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Case Reports
. 2024 Sep 26;16(9):e70247.
doi: 10.7759/cureus.70247. eCollection 2024 Sep.

Squamous Cell Carcinoma of the Pancreas: A Case Report

Alessandra Nagar  1 , Anitha Rao  2 , Petr Protiva  3
Affiliations
Case Reports

Squamous Cell Carcinoma of the Pancreas: A Case Report

Alessandra Nagar et al. Cureus. .

Abstract

Primary squamous cell carcinoma (PSCC) of the pancreas is a rare malignancy with poor prognosis and unclear management. Here, we present the case of a patient with PSCC, review the literature, identify areas of therapeutic uncertainty, and conclude that more clinical and molecular data are needed to improve the prognosis of this rare malignancy.

Keywords: carcinoma pancreas; pancreatic malignancy; squamous cell carcinoma; survival analysis; tumor imaging.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. A case of primary squamous carcinoma of the pancreas.
A: CT scan of the abdomen demonstrating a 7 cm pancreatic mass causing duodenal and biliary compression (arrows). B: The same neoplasm imaged by endoscopic ultrasound showing a hypodense mass (arrows). C: Hematoxylin-eosin stains of fine-needle biopsy of the mass showed a poorly differentiated tumor with immunostaining positive for cytokeratin and P40 (D: P40 stain is shown), magnification: ×200.
See this image and copyright information in PMC

References

    1. Primary squamous cell carcinoma of the pancreas with a large pseudocyst of the pancreas as the first manifestation: a rare case report and literature review. Qiu X, Meng Y, Lu M, Tian C, Wang M, Zhang J. BMC Gastroenterol. 2021;21:208. - PMC - PubMed
    1. Squamous cell carcinoma of the pancreas. Brown HA, Dotto J, Robert M, Salem RR. J Clin Gastroenterol. 2005;39:915–919. - PubMed
    1. Primary squamous cell carcinoma of pancreas: a population-based study. Qin WX, Wu Y, Liu J, et al. Gland Surg. 2021;10:1029–1037. - PMC - PubMed
    1. Pancreatic adenocarcinoma. Vareedayah AA, Alkaade S, Taylor JR. http://pubmed.ncbi.nlm.nih.gov/30228728/ Mo Med. 2018;115:230–235. - PMC - PubMed
    1. Pancreatic squamous cell carcinoma: a population-based study of epidemiology, clinicopathologic characteristics and outcomes. Makarova-Rusher OV, Ulahannan S, Greten TF, Duffy A. Pancreas. 2016;45:1432–1437. - PMC - PubMed

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