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Observational Study
. 2024 Oct 1;72(10):1501-1505.
doi: 10.4103/IJO.IJO_3237_23. Epub 2024 Sep 27.

Volume measurement of the vitrectomised eye and its applications in practice

Surbhi Agrawal  1 , P Mahesh Shanmugam  1 , Divyansh Kailashchandra Mishra  1 , Rajesh Ramanjulu  1 , H N Ravishankar  2 , Pradeep Sagar  2 , Harshal Sahare  2 , Shwetha Suryakanth  1
Affiliations
Observational Study

Volume measurement of the vitrectomised eye and its applications in practice

Surbhi Agrawal et al. Indian J Ophthalmol. .

Abstract

Purpose: To estimate the vitreous cavity replacement volume after pars plana vitrectomy and analyze its correlation with axial length and refractive error.

Methods: Observational cross-sectional study on 103 eyes undergoing vitrectomy. Fluid-air exchange was performed using a soft-tip cannula connected to a PVC tubing, the distal end of which opened into a 10-cc syringe without the plunger. The collected fluid was measured (and correction factors applied) to estimate the vitreous cavity volume.

Results: The mean axial length of 103 eyes was 23.43 ± 1.54 mm. The mean vitreous cavity volume was 4.46 ± 0.83 mL (2.8-8.1 mL). There was a strong positive correlation between axial length and vitreous volume, which was stronger for pseudophakic and aphakic groups than for phakic groups.

Conclusion: Accurate assessment of vitreous cavity volume can enable precise quantification of tamponade, intravitreal drugs, and intravitreal chemotherapeutic agents. This will allow better surgical outcomes, decreased toxicity, and increased cost-effectiveness due to lesser wastage.

Objective: To estimate the vitreous cavity replacement volume after pars plana vitrectomy and analyze its correlation with axial length and refractive error.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
A soft-tip cannula was connected to a fixed-length PVC tubing, and the other end of this tube opened into a 10-cc syringe (with the plunger removed); (a). Fluid collected in the syringe was measured to obtain volume x (b)
Figure 2
Figure 2
Flow diagram to demonstrate the various fluid compartments relevant to the intraoperative measurement of vitrectomised eye volume. x is the volume of fluid collected after fluid-air exchange. It includes fluid in the eye and fluid in the infusion tubing. y is the volume of fluid in the infusion tubing and was measured using the technique described in the supplemental video. z is the volume of the vitrectomised eye, obtained as follows, z = x − y
Figure 3
Figure 3
Scatter plot for measured vitreous cavity volume (y-axis) as a function of axial length (y-axis). Graphs were plotted for the entire study population (left), phakic eyes (middle), and pseudophakic eyes (right). Aphakic eyes (n = 9) did not have a sufficient sample size due to the general rarity of such patients in modern ophthalmology
Figure 4
Figure 4
Scatter plot for measured vitreous cavity volume (y-axis) as a function of refractive error (y-axis)
See this image and copyright information in PMC

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