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Review
. 2024 Sep 20;13(18):5577.
doi: 10.3390/jcm13185577.

Surgical Innovations to Protect Fertility from Oncologic Pelvic Radiation Therapy: Ovarian Transposition and Uterine Fixation

Ariella Yazdani  1 , Katherine Moran Sweterlitsch  2 , Hanna Kim  1 , Rebecca L Flyckt  3 , Mindy S Christianson  1
Affiliations
Review

Surgical Innovations to Protect Fertility from Oncologic Pelvic Radiation Therapy: Ovarian Transposition and Uterine Fixation

Ariella Yazdani et al. J Clin Med. .

Abstract

As oncologic therapy continues to advance, survivorship care has widened the realm of possibilities for quality-of-life improvements, including fertility preservation and restoration. We aim to summarize the current and future directions of fertility preservation techniques for patients facing gonadotoxic medical therapies who desire pregnancy after their condition is treated. This review of both ovarian and uterine transposition highlights the present roles, techniques, and fertility outcomes of the two fertility preservation treatment modalities designed to protect reproductive organs from harmful pelvic radiation. Current evidence shows that ovarian transposition preserves ovarian function for patients with localized pelvic radiation demonstrating the most successful return of fertility. Uterine transposition holds great promise for patients desiring to conceive and carry a full-term pregnancy after radiation therapy. With ongoing advancements in oncologic treatments leading to increased survival rates, fertility is increasingly becoming a key survivorship issue. Patients can anticipate counseling about these fertility preservation surgical techniques that protect both the ovaries as well as the uterus from harmful pelvic radiation.

Keywords: fertility preservation; oophoropexy; ovarian transposition; uterine transposition.

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Conflict of interest statement

The authors declare no conflict of interest.

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