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Clinical Trial
. 1979 Nov-Dec;63(11-12):2071-5.

Cis-dichlorodiammineplatinum(II) in metastatic soft tissue sarcomas

C P Karakousis, O A Holtermann, E D Holyoke
  • PMID: 393389
Clinical Trial

Cis-dichlorodiammineplatinum(II) in metastatic soft tissue sarcomas

C P Karakousis et al. Cancer Treat Rep. 1979 Nov-Dec.

Abstract

cis-Dichlorodiammineplatinum(II) was given to 13 patients with metastatic sarcomas following failure in two previous chemotherapy protocols. Two of these patients had complete regression which lasted 6 months in one patient and is still present after 8 months in the other. One patient had a greater than 50% regression which lasted 5 months. Three patients had disease stabilization for 2 months each. cis-Dichlorodiammineplatinum(II), as a single agent, was well-tolerated with no significant renal or auditory toxicity.

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