doi: 10.1126/science.39341.
Erythrosin B inhibition of neurotransmitter accumulation by rat brain homogenate
- PMID: 39341
- DOI: 10.1126/science.39341
Item in Clipboard
Erythrosin B inhibition of neurotransmitter accumulation by rat brain homogenate
Science.
.
Abstract
A mixture of seven food dyes inhibited the accumulation of eight neurotransmitters or neurotransmitter precursors by rat brain homogenate. At a low concentration (1 microgram per milliliter), erythrosin B (FD&C red 3) was the only dye that inhibited dopamine accumulation. Erythrosin also was effective in decreasing the accumulation of all the other transmitter substances, suggesting that the inhibition is nonspecific and probably secondary to general membrane alteration.
Similar articles
-
Neurotransmitter release and nerve terminal morphology at the frog neuromuscular junction affected by the dye Erythrosin B.J Physiol. 1983 Jan;334:47-63. doi: 10.1113/jphysiol.1983.sp014479. J Physiol. 1983. PMID: 6134825 Free PMC article.
-
Artificial food colors and childhood behavior disorders.Bull N Y Acad Med. 1982 Apr;58(3):275-95. Bull N Y Acad Med. 1982. PMID: 6288159 Free PMC article. Review. No abstract available.
-
Food dye, erythrosin B, inhibits ATP-dependent calcium ion transport by brain microsomes.Biochem Int. 1984 Nov;9(5):557-62. Biochem Int. 1984. PMID: 6098274
-
Erythrosin B inhibits dopamine transport in rat caudate synaptosomes.Science. 1979 Jul 27;205(4404):410-2. doi: 10.1126/science.451609. Science. 1979. PMID: 451609
-
Neurotoxicants and central catecholamine systems.Neurotoxicology. 1987 Spring;8(1):123-39. Neurotoxicology. 1987. PMID: 3031560 Review.
Cited by
-
Neurotransmitter release and nerve terminal morphology at the frog neuromuscular junction affected by the dye Erythrosin B.J Physiol. 1983 Jan;334:47-63. doi: 10.1113/jphysiol.1983.sp014479. J Physiol. 1983. PMID: 6134825 Free PMC article.
-
Mammalian cerebral cortical tissue responds to low-intensity visible light.Proc Natl Acad Sci U S A. 1988 Dec;85(23):9322-6. doi: 10.1073/pnas.85.23.9322. Proc Natl Acad Sci U S A. 1988. PMID: 3194426 Free PMC article.
-
Photodynamic effects of erythrosine on the smooth muscle cells of guinea-pig taenia coli.Br J Pharmacol. 1984 Oct;83(2):555-66. doi: 10.1111/j.1476-5381.1984.tb16520.x. Br J Pharmacol. 1984. PMID: 6148988 Free PMC article.
-
Differential inhibition of brain specific [3H]flunitrazepam binding by several types of dyes.Neurochem Res. 1983 Sep;8(9):1177-83. doi: 10.1007/BF00964931. Neurochem Res. 1983. PMID: 6633792
-
Artificial food colors and childhood behavior disorders.Bull N Y Acad Med. 1982 Apr;58(3):275-95. Bull N Y Acad Med. 1982. PMID: 6288159 Free PMC article. Review. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
